The 100 most highly cited papers of all time

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To mark the anniversary, Nature magazine asked Thomson Reuters to list the 100 most highly cited papers of all time. The search covered all of Thomson Reuter’s Web of Science, an online version of the SCI that also includes databases covering the social sciences, arts and humanities, conference proceedings and some books. It lists papers published from 1900 to the present day.

 
Title of the paperRankAsunto
The assessment and analysis of handedness: the Edinburgh inventory.61Psychology/psychiatryVer Más
Estimation of concentration of low-density lipoprotein cholesterol in plasma - without use of preparative ultracentrifuge.62MedicineVer Más
Primer-directed enzymatic amplification of DNA with a thermostable DNA polymerase.63Biology lab techniqueVer Más
Multiple range and multiple F tests.64Mathematics/statisticsVer Más
Electric field effect in atomically thin carbon films.65PhysicsVer Más
Tissue sulfhydryl groups.66Biology lab techniqueVer Más
Isolation of mononuclear cells and granulocytes from human blood.67Biology lab techniqueVer Más
The measurement of observer agreement for categorical data.68Mathematics/statisticsVer Más
Crystallography & NMR system: a new software suite for macromolecular structure determination.69CrystallographyVer Más
Gaussian-basis sets for use in correlated molecular calculations. 1. The atoms boron through neon and hydrogen.70Mathematics/statisticsVer Más
PROCHECK: a program to check the stereochemical quality of protein structures.71CrystallographyVer Más
The MOS 36-item short-form health survey (SF-36): I. Conceptual framework and item selection.72MedicineVer Más
A new look at statistical-model identification.73Mathematics/statisticsVer Más
Improved M13 phage cloning vectors and host strains — nucleotide-sequences of the M13mp18 and pUC19 vectors74Biology lab techniqueVer Más
A comprehensive set of sequence-analysis programs for the vax.75BioinformaticsVer Más
MODELTEST: Testing the model of DNA.76BioinformaticsVer Más
From ultrasoft pseudopotentials to the projector augmented-wave method.77Physical chemistryVer Más
Use of avidin-biotin-peroxidase complex (ABC) in immunoperoxidase techniques: a comparison between ABC and unlabeled antibody (PAP) procedures.78Biology lab techniqueVer Más
Comparison of simple potential functions for simulating liquid water.79Biology lab techniqueVer Más
The development and use of quantum-mechanical molecular-models. 76. AM1: a new general-purpose quantum-mechanical molecular-model80Physical chemistryVer Más

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