The 100 most highly cited papers of all time

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To mark the anniversary, Nature magazine asked Thomson Reuters to list the 100 most highly cited papers of all time. The search covered all of Thomson Reuter’s Web of Science, an online version of the SCI that also includes databases covering the social sciences, arts and humanities, conference proceedings and some books. It lists papers published from 1900 to the present day.

 
Title of the paperRankOggetto
Confidence limits on phylogenies: an approach using the bootstrap41PhylogeneticsVedi di più
A new generation of Ca2+ indicators with greatly improved fluorescence properties42Biology lab techniqueVedi di più
Efficient iterative schemes for ab initio total-energy calculations using a plane-wave basis set.43Physical chemistryVedi di più
High-resolution 2-dimensional electrophoresis of proteins.44Biology lab techniqueVedi di più
MEGA4: Molecular Evolutionary Genetics Analysis (MEGA) software version 4.0.45PhylogeneticsVedi di più
Fuzzy sets.46Mathematics/statisticsVedi di più
Phase annealing in SHELX-90: direct methods for larger structures.47CrystallographyVedi di più
Clinical diagnosis of Alzheimer’s disease: Report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer’s Disease.48MedicineVedi di più
Special points for Brillouin-zone integrations.49PhysicsVedi di più
Study of the conditions and mechanism of the diphenylamine reaction for the colorimetric estimation of deoxyribonucleic acid.50Biology lab techniqueVedi di più
The CES-D scale: a self-report depression scale for research in the general population.51Psychology/psychiatryVedi di più
Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches.52Biology lab techniqueVedi di più
A rating scale for depression.53Psychology/psychiatryVedi di più
An inventory for measuring depression.54Psychology/psychiatryVedi di più
A simple method for displaying the hydropathic character of a protein.55Biology lab techniqueVedi di più
Determination of serum proteins by means of the biuret reaction.56Biology lab techniqueVedi di più
Maximum likelihood from incomplete data via EM algorithm.57Mathematics/statisticsVedi di più
Equation of state calculations by fast computing machines.58Mathematics/statisticsVedi di più
Controlling the false discovery rate: a practical and powerful approach to multiple testing.59Mathematics/statisticsVedi di più
Measurement of protein using bicinchoninic acid.60Biology lab techniqueVedi di più