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Federal Register / Vol. 86, No. 36 / Thursday, February 25, 2021 / Notices clinical utility has been constrained, in part, by dose-limiting toxicity following systemic administration and the need for repeated dosing. The subject invention addresses these limitations through synthetic IL15/21 sequences which incorporate flexible linker regions and cell membrane anchors. T
cells engineered to express these constructs experience autocrine IL15/
21 signaling leading to enhanced antitumor function in vivo.
This Notice is made in accordance with 35 U.S.C. 209 and 37 CFR part 404.
The prospective exclusive license will be royalty bearing, and the prospective exclusive license may be granted unless within fifteen 15 days from the date of this published Notice, the National Cancer Institute receives written evidence and argument establishing that the grant of the license would not be consistent with the requirements of 35
U.S.C. 209 and 37 CFR part 404.
In response to this Notice, the public may file comments or objections.
Comments and objections, other than those in the form of a license application, will not be treated confidentially and may be made publicly available.
License applications submitted in response to this Notice will be presumed to contain business confidential information and any release of information from these license applications will be made only as required and upon a request under the Freedom of Information Act, 5 U.S.C.
552.
Dated: February 12, 2021.
Richard U. Rodriguez, Associate Director, Technology Transfer Center, National Cancer Institute.
FR Doc. 202103873 Filed 22421; 8:45 am BILLING CODE 414001P

DEPARTMENT OF HEALTH AND
HUMAN SERVICES
National Institutes of Health Submission for OMB Review; 30-Day Comment Request; CareerTrac AGENCY:

National Institutes of Health,
HHS.

ACTION:

after October 1, 1995, unless it displays a currently valid OMB control number.
In compliance with Section 3507a1D of the Paperwork Reduction Act of 1995, the National Institutes of Health NIH has submitted to the Office of Management and Budget OMB a request for review and approval of the information collection listed below.
Proposed Collection: CareerTrac09250568expiration date April 30, 2021, REVISION, Fogarty International Center FIC, National Institute of Environmental Health Sciences NIEHS, National Cancer Institute NCI, National Institute of Diabetes and Digestive Kidney Diseases, NIDDK, National Institutes of Health NIH.
Need and Use of Information Collection: The purpose of this data collection system is to track, evaluate and report short and long-term outputs, outcomes and impacts of trainees involved in health research training programs-specifically tracking this for at least ten years following training by having Principal Investigators enter data after trainees have completed the program. The data collection system provides a streamlined, web-based application permitting principal investigators to record career achievement progress by trainee on a voluntary basis. FIC, NCI, NIDDK, and NIEHS management will use this data to monitor, evaluate and adjust grants to ensure desired outcomes are achieved, comply with OMB Part requirements, respond to congressional inquiries, and as a guide to inform future strategic and management decisions regarding the grant program.
OMB approval is requested for 3
years. There are no costs to respondents other than their time. The total estimated annualized burden hours are 12,705.

Notice.

In compliance with the Paperwork Reduction Act of 1995, the National Institutes of Health NIH has submitted to the Office of Management and Budget OMB a request for review and approval of the information collection listed below.
DATES: Comments regarding this information collection are best assured of having their full effect if received within 30-days of the date of this publication.
SUMMARY:

Written comments and recommendations for the proposed information collection should be sent within 30 days of publication of this notice to www.reginfo.gov/public/do/
PRAMain. Find this particular information collection by selecting Currently under 30-day ReviewOpen for Public Comments or by using the search function.
FOR FURTHER INFORMATION CONTACT: To request more information on the proposed project or to obtain a copy of the data collection plans and instruments, contact: Dr. Kristi Pettibone, Health Scientist Administrator, Program Analysis Branch, Division of Extramural Research and Training, NIEHS, NIH, 560 Davis Dr., Morrisville, NC 27560, or call nontoll-free number 984 2873303 or Email your request, including your address to: pettibonekg@niehs.nih.gov.
SUPPLEMENTARY INFORMATION: This proposed information collection was previously published in the Federal Register on December 12, 2020, page 7949379494 64 FR 15367 and allowed 60 days for public comment. No public comments were received. The purpose of this notice is to allow an additional 30 days for public comment.
The Fogarty International Center FIC, National Cancer Institute NCI, National Institute of Diabetes and Digestive and Kidney Diseases NIDDK, and National Institute of Environmental Health Sciences NIEHS, may not conduct or sponsor, and the respondent is not required to respond to, an information collection that has been extended, revised, or implemented on or ADDRESSES:

ESTIMATED ANNUALIZED BURDEN HOURS
Number of respondents
Type of respondent
FIC Grantee
NIEHS Grantee
NCI CRCHD Grantee
NCI D43 Grantee
Superfund Grantee

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Number of responses per respondent
90
60
244
20
30

E:FRFM25FEN1.SGM

20
45
22
22
105

25FEN1

Average burden per response in hours 40/60
40/60
40/60
40/60
40/60

Total annual burden hour 1,200
1,800
3,579
293
2,100