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Federal Register / Vol. 86, No. 44 / Tuesday, March 9, 2021 / Rules and Regulations
Creek, Gasconade River, Huzzah Creek, Meramec River, Niangua River, and Osage Fork of the Gasconade River figure 1. The Meramec River watershed, which includes the Big River
and Courtois Creek, drains directly into the Mississippi River; whereas all of the other watersheds in the Missouri DPS
drain directly into the Missouri River.
Please refer to our April 4, 2019,
proposed rule 84 FR 13223 for a summary of species background information available to the Service at the time that it was published.

Regulatory and Analytical Framework
A The present or threatened destruction, modification, or curtailment of its habitat or range;
B Overutilization for commercial, recreational, scientific, or educational purposes;
C Disease or predation;
D The inadequacy of existing regulatory mechanisms; or E Other natural or manmade factors affecting its continued existence.
These factors represent broad categories of natural or human-caused actions or conditions that could have an effect on a species continued existence.
In evaluating these actions and conditions, we look for those that may have a negative effect on individuals of the species, as well as other actions or conditions that may ameliorate any negative effects or may have positive effects.
We use the term threat to refer in general to actions or conditions that are
known to or are reasonably likely to negatively affect individuals of a species. The term threat includes actions or conditions that have a direct impact on individuals, as well as those that affect individuals through alteration of their habitat or required resources.
The term threat may encompass either together or separatelythe source of the action or condition or the action or condition itself.
However, the mere identification of any threats does not necessarily mean that the species meets the statutory definition of an endangered species or a threatened species. In determining whether a species meets either definition, we must evaluate all identified threats by considering the expected response by the species, and the effects of the threatsin light of those actions and conditions that will ameliorate the threatson an
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Regulatory Framework Section 4 of the Act 16 U.S.C. 1533
and its implementing regulations 50
CFR part 424 set forth the procedures for determining whether a species is an endangered species or a threatened species. The Act defines an endangered species as a species that is in danger of extinction throughout all or a significant portion of its range, and a threatened species as a species that is likely to become an endangered species within the foreseeable future throughout all or a significant portion of its range. The Act requires that we determine whether any species is an endangered species or a threatened species because of any of the following factors:

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