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REGISTER
VO LU M I 14

NUM M I !

,
Washington, Friday November 18, 1949

TITLE 7 AGRICULTURE
Chapter I Production and Marketing Administration Standards, Inspec tions, Marketing Practices, Depart ment of Agriculture Interpretation 18
P art 162R egulations for the E n
forcement of the F ederal I nsecticide, F ungicide, and R odenticide Act interpretation w ith respect to warn ing, CAUTION AND ANTIDOTE STATEMENTS

REQUIRED TO APPEAR ON LABELS OF ECO
NOMIC POISONS

Pursuant to the authority vested in me by 162.3 of the regulations 7 CFR
162.3 under the Federal Insecticide, Fungicide, and Rodenticide Act 7 U. S. C.
135-135k, Interpretation No. 18, with respect to warning, caution, and antidote statements required to appear on the la bels of economic poisons is hereby issued, as 162.116 of Part 162, Title 7, Code of Federal Regulations, to read as follows:
162.116 Interpretation with respect to warning, caution, and antidote state ments required to appear on labels of economic poisonsa Requirements of the act. Section 2u 2 d of the act provides that an economic poison is mis branded if its label does not contain a warning or caution statement which may be necessary and if complied with ade quate to prevent injury to living man arid other vertebrate animals, vegetation, and useful invertebrate animals. Sec tion 3 a 3 of the act requires that any economic poison which contains any substance or substances in quantities highly toxic to man must bear on the label the skull and crossbones, the word poison in red, and an a n t i d o t e statement.
b Categories of toxicity and general provisions as to statements required for economic poisons therein. 1 Four gen eral categories of toxicity of economic poisons are recognized. The first is the highly toxic class as defined in 162.8.
The second is the class immediately below the highly toxic, and in general in cludes formulations having toxicities down to one-tenth those of the highly toxic class. The third group embraces products having hazards below class two but to a degree which still requires some
cautions and usually includes toxicities down to about one-tenth of those in class two. The fourth class is compara tively free from danger.
2 Products in the categories speci fied in subparagraph 1 of this para graph are to be distinguished from each other by the following general scheme:
i Highly toxic products are required by the act to be labeled with the skull and crossbones, the word Poison in red and an antidote statement. The antidote statement should include the sentence Call A Physician Immediately and should be followed by the word Warning and a statement of the major hazards of use with instructions for handling to reduce chances of injury.
ii Labels of products which fall in the second category should carry warn ing statements equivalent to those re quired for highly toxic materials, but they do not need to bear the skull and crossbones, the word Poison, or an antidote statement.
iii Labels of products in the third category should carry the word Cau tion and statements Indicating the principal hazards of use and means of avoiding them. Use of the skull and crossbones, the word Poison and anti dote statements are not necessary for these products.
iv No warning, caution, or antidote statements are required for the few for mulations in the fourth category.
c Miscellaneous provisions.
1 Warning or caution statements on the labels of economic poisons must give con cise and easily understood warnings as to the hazards associated with use of the products, together with instructions to be followed to insure adequate protec tion. Precautionary labeling should be aimed directly at the hazards, associated with the formulation as it is sold to and used by the customer, whether it is suit able for use directly or must be diluted or mixed prior to application. If a prod uct is intended for use on food crops, its application should be limited by appro priate statement to such time as will avoid danger of food contamination from spray residue. Even if not covered in this interpretation, unique hazards asso ciated with the use of any productsuch as the possibility of injury to beneficial crops from careless application of herContinued on next page
CONTENTS
Page
Agriculture Department
See Production and Marketing Ad ministration.
Alien Property, Office of
Notices:
Vesting orders, etc.:
Andreae, Irmgard_________
Edelblut, Joseph__________
Lowenberg, Kurt__________
Lucchesi, Clementina, et al_
Society for Care of German Seamen in Port of New York__________________

7002
7002
7002
7002
7001

Civil Aeronautics Administra tion
Rules and regulations:
Civil airways; designation, re designation and revocation__ 6992
Control areas, control zones and reporting points, designation;
miscellaneous amendments. _ 6993
Federal aid to public agencies for development of public air ports; project costs________ 6992
Civil Aeronautics Board
Notices:
Monarch Air Lines, Inc. and Challenger Airlines Co.; hear ing ----------------- :_________ 6997
Resort Airlines, Inc.; certifi cated operations__________ 6998
Commerce Department
See Civil Aeronautics Administra tion.
Customs Bureau
Rules and regulations:
Air commerce regulations; land ing requirements, place of landing__________________ 6994
Articles conditionally free, sub ject to a reduced rate, etc.;
basic duty exemption____ _
6994
Enforcement of customs and navigation laws; basic duty exemption________________ 6994
Federal Power Commission
Notices:
Hearings, etc.:
California Oregon Power Co_ 6899
Central Maine Power Co___ 6999
Fresno Irrigation District and Pacific Gas and Electric Co_ 6999
Federal Security Agency
See Public Health Service.
6985